Gf. Dervin, SKELETAL FIXATION OF GRADE IIIB TIBIAL FRACTURES - THE POTENTIAL OF METAANALYSIS, Clinical orthopaedics and related research, (332), 1996, pp. 10-15
Contemporary management of Grade IIIB open tibial fractures has evolve
d to include intravenous antibiotics, thorough interval surgical debri
dement, rigid skeletal fixation, early local or free tissue myoplasty,
and liberal use of autogenous bone graft beneath a clean, stable woun
d. External fixation has been the skeletal stabilization of choice wit
h the lowest reported deep sepsis fates, Pin tract infection, malunion
, and nonunion have complicated its use, Static unreamed locked nailin
g is an alternative treatment that has been successfully used in lower
grade open tibial fractures. A metaanalysis of the literature was und
ertaken to determine whether there was evidence favoring 1 method of s
keletal fixation. Inclusion criteria were restricted to studies that m
ere randomized to either external fixation or unreamed intramedullary
nail methods and that used a strict definition of Grade IIIB to includ
e muscle transfer for soft tissue coverage. Two studies were identifie
d and combined to show no difference in deep sepsis rate, Intramedulla
ry nailing significantly shortened union time whereas external fixatio
n showed a trend toward a higher incidence of malunion and superficial
sepsis, More well designed randomized studies would add to this initi
al effort and yield more compelling evidence for either form of fixati
on.