T. Lofqvist et al., ORTHOPEDIC-SURGERY IN HEMOPHILIA - 20 YEARS EXPERIENCE IN SWEDEN, Clinical orthopaedics and related research, (332), 1996, pp. 232-241
At the International Hemophilia Center, Malmo, Sweden, which serves a
large proportion of the Swedish hemophilia population, 98 orthopaedic
surgical procedures were performed from 1970 to 1989 in 66 patients ra
nging in age from 6 to 71 gears, The most common procedures were knee
synovectomy, elbow synovectomy in combination with resection of the ra
dial head, and total hip replacement, Comparing the 2 decades of the p
eriod, 3 differences were observed: a decreasing need of surgery, an i
ncreasing average age of the patients, and a change in the kinds of op
erations performed, Knee synovectomy and achillotenotomy were most fre
quent during the 1970s, whereas elbow synovectomy with resection of th
e radial head and total hip replacement were most frequent during the
1980s, Owing to the availability of regular factor replacement therapy
as practiced at the Malmo Center, the situation of patients with hemo
philia has improved dramatically during the last 2 decades, In the aut
hors' opinion, it is now possible to avoid hemophilic arthropathy almo
st completely by giving effective continuous prophylaxis from an early
age, In all likelihood, this is the explanation of the changing pictu
re of orthopaedic surgery in patients with hemophilia today.