H. Kuchiwaki et al., INTRAOPERATIVE LASER FLOWMETRY REFLECTS LEVELS OF CEREBRAL BLOOD-FLOWDURING NEUROSURGICAL PROCEDURES, Neurological research, 18(5), 1996, pp. 457-461
Changes in cerebral blood flow (CBF) during craniotomies (mean 62.2 ye
ars, n = 31) were studied using a laser flowmeter (LFM) to evaluate th
e utility in CBF monitoring. A small flat probe was applied to the bra
in surface near the surgical field. The output voltage from LFM was re
corded as CBF changes. The percent change in CBF was calculated using
the formula [intrasurgical-CBF-control-CBF]/control-CBF x 100. Postope
rative neurologic status was evaluated. Control-CBF values were simila
r among the groups representing different pathologies. The mean CBF de
crease ranged from -7.3% following phenytoin injection (n = 9) to -32.
7% during induced intrathoracic pressure (n = 10). The mean CBF increa
se was 41.4% following vascular anastomosis. A decrease > 50% for more
than 15 min was associated with a severe permanent neurologic deficit
. The CBF monitoring using an LFM during craniotomy may be useful in d
etecting clinical CBF levels for reducing post-operative neurological
deficits.