G. Kanra et al., MICROORGANISMS INVOLVED IN ACUTE BACTERIAL-MENINGITIS IN CHILDREN ANDTHE ROLE OF HAEMOPHILUS-INFLUENZAE, Turkish Journal of Pediatrics, 38(4), 1996, pp. 407-412
Acute bacterial meningitis (ABM) is an important cause of mortality an
d neurological damage in children. Documentation of the etiological ag
ents is very important both for the treatment of patients and for prop
hylactic approaches. H.influenzae, N.meningitidis and S.pneumoniae are
the three major pathogens involved in ABM. In Turkey for many years H
.influenzae has not been isolated in cerebrospinal fluid (CSF) specime
ns. In order to show the bacteria involved in ABM in our hospital and
to see the role of H.influenzae, we investigated the CSF of 59 patient
s with bacterial meningitis using Gram and Wayson stains, culture and
latex agglutination techniques. The agents were determined in 38 (64.4
%) specimens by using culture positivity in 30 (50.8%), and latex or s
tain positivity in eight (13.6%) specimens. The microorganisms causing
ABM included S.pneumoniae (25.6%), gram-negative enteric bacilli (17.
9%), N.meningitis (12.8%), alpha hemolytic streptococci (10.3%), H.inf
luenzae (10.3%), nonfermentative gram-negative bacilli (5.1%), candida
spp. (5.1%), group B streptococci (2.6%), coagulase negative staphylo
cocci (2.6%), S.aureus (2.6%) and pseudomonas spp, (5.1%). In this stu
dy it has been shown that H.influenzae can cause ABM in Turkish childr
en. Multicentric studies from different parts of Turkey will be helpfu
l in showing the real incidence in our country.