SERUM ERYTHROPOIETIN AND GRANULOCYTE-MACROPHAGE-COLONY STIMULATING FACTOR LEVELS WITH MEGADOSE METHYLPREDNISOLONE TREATMENT

Authors
SAYLI TR OZSOYLU S
Citation
Tr. Sayli et S. Ozsoylu, SERUM ERYTHROPOIETIN AND GRANULOCYTE-MACROPHAGE-COLONY STIMULATING FACTOR LEVELS WITH MEGADOSE METHYLPREDNISOLONE TREATMENT, Turkish Journal of Pediatrics, 38(4), 1996, pp. 491-495
Citations number
16
Categorie Soggetti
Pediatrics
Journal title
Turkish Journal of Pediatrics → ACNP
ISSN journal
00414301
Volume
38
Issue
4
Year of publication
1996
Pages
491 - 495
Database
ISI
SICI code
0041-4301(1996)38:4<491:SEAGSF>2.0.ZU;2-T
Abstract
Serum erythropoietin (EPO) and granulocyte-macrophage-colony stimulati ng factor (GM-CSF) levels were determined in 12 children with acute an d seven with chronic idiopathic thrombocytopenic purpura (ITP) prior t o and during megadose methylprednisolone (MDMP) treatment by using enz yme-linked immunosorbant assay (ELISA) kits. It was shown that elevati on of EPO and GM-CSF levels was correlated with an increase in hemoglo bin (Hb), packed cell volume (PCV), red blood cell (RBC), leukocyte (L eu), polymorphonuclear leukocyte (PMN) and monocyte (Mo) counts during MDMP treatment.