Loss of consciousness and falling are the key features of syncope. Com
mon accompaniments include tonic and myoclonic muscle activity, eye de
viations, automatisms, vocalizations and hallucinations which may rend
er the distinction from epileptic seizures difficult. Differential dia
gnosis is based on the specific features and not the mere presence of
these phenomena. Recognition of syncope depends also on accurate infor
mation about precipitants, premonitory symptoms and postictal events:
the absence of postictal confusion has been identified as the single m
ost powerful factor discriminating syncope from epileptic seizures whe
reas incontinence and head injury are common in both conditions, inves
tigations such as electroencephalogram, tilt testing and posticial pro
lactin or creatine kinase levels may he helpful but are never diagnost
ic in isolation, Exceptionally, hypoxic and epileptic mechanisms inter
act within a single attack.