Necrotizing enterocolitis (NEC) is the most common surgical emergency
in the newborn. Up to half of babies with NEC develop advanced disease
requiring surgical intervention. Options include peritoneal drainage
under local anaesthetic, enterostomy only, resection and enterostomies
, and resection with primary anastomosis, Resection with enterostomies
is favoured by many paediatric surgeons but management of neonatal en
terostomies can be difficult. The outcome of 26 infants undergoing sur
gery for advanced NEC over a 2-year period is reviewed. Resection and
primary anastomosis was possible in 18 infants of whom two (11%) died,
Recurrent NEC developed in four (22%) and strictures in three (17%) o
f these infants. An initial enterostomy was fashioned in eight infants
, three following resection of necrotic intestine and five as a proxim
al diverting stoma in infants with pan-intestinal involvement. Five of
these eight infants died (63%), giving an overall mortality of 27%. P
rimary anastomosis is an effective procedure following resection of gr
ossly involved intestine in infants with NEC. The mortality and morbid
ity in this series compared well with those reported for staged proced
ures.