Objective: Is it possible to successfully treat sexual disturbances re
lated to an estrogen deficiency syndrome with estrogens? Methods: For
4 months, sexual dysfunctions (loss of libido, dyspareunia, difficulti
es in experiencing orgasm) were treated with a transdermal system - th
e estrogen patch - in one group cyclically and in a second continually
. Women with uterus got I mg/day norethisterone acetate for 12 days a
month. Results: By estrogen therapy alone, success was seen in 40/41%
for loss of libido, in 75/56% for dyspareunia and in 47/25% for diffic
ulties of orgasm. Conclusions: In spite of the complexity of the biops
ychosocial causes of the sexual disturbances in relation with an estro
gen deficiency syndrome, the replacement therapy is successful in many
cases.