FLAD (SINR) MUTATIONS AFFECT SIGD-DEPENDENT FUNCTIONS AT MULTIPLE POINTS IN BACILLUS-SUBTILIS

Authors
RASHID MH SEKIGUCHI J
Citation
Mh. Rashid et J. Sekiguchi, FLAD (SINR) MUTATIONS AFFECT SIGD-DEPENDENT FUNCTIONS AT MULTIPLE POINTS IN BACILLUS-SUBTILIS, Journal of bacteriology, 178(22), 1996, pp. 6640-6643
Citations number
33
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
178
Issue
22
Year of publication
1996
Pages
6640 - 6643
Database
ISI
SICI code
0021-9193(1996)178:22<6640:F(MASF>2.0.ZU;2-V
Abstract
A flaD (sinR) null mutation depressed sigD-lacZ expression only two- t o fourfold, whereas a flaD1 point mutation depressed it almost complet ely. Introduction of pHYSigD, a sigma(D)-overproducing plasmid, correc ted the filamentous phenotype common to both sinR mutants; autolysin s ynthesis was restored partially and completely in the flaD1 and flaD ( sinR) null strains, respectively. Flagellin synthesis and motility wer e not restored at all in either strain.