Sd. Elakovich et J. Yang, STRUCTURES AND ALLELOPATHIC EFFECTS OF NUPHAR ALKALOIDS - NUPHAROLUTINE AND 6,6'-DIHYDROXYTHIOBINUPHARIDINE, Journal of chemical ecology, 22(12), 1996, pp. 2209-2219
Two of the major Nuphar alkaloids, nupharolutine and 6,6'-dihydroxythi
obinupharidine, were isolated from the aquatic perennial herb Nuphar l
utea (L.) Sibth. & Sm., yellow water lily. In a lettuce seedling bioas
say of the two pure compounds, the former was inactive and the latter
was highly inhibitory of radicle elongation at concentrations greater
than 2 ppm. Structures and stereochemistry of the two compounds were c
onfirmed by DEPT, H-1-H-1 COSY, H-1-C-13 COSY, and H-1-H-1 NOESY exper
iments.