In the years 1983-84, the Swedish Committee for the Prevention and Tre
atment of Depression (PTD) offered an educational programme to all gen
eral practitioners (GP:s) on the Swedish island of Gotland. The educat
ion has been shown to lead to a significant decrease in inpatient care
, morbidity, mortality and costs caused by depressive illness on the i
sland. Unspecific medication decreased and specific anti-depressive me
dication increased. A scrutiny of all suicides on Gotland during the 1
980s revealed that the overall decrease in suicides as a result of the
educational programme was caused mainly by the decrease in suicides c
ommitted by female suicidants with recognized major depression and in
contact with general practitioners. This was expected. However, the nu
mber of male suicides was almost unaffected by the educational program
me, as well as improvement in the GPs ability to diagnose and treat de
pression. This was unexpected. We believe that the reason for this is
that male depressive suicidants are possibly not reached by the medica
l health care system. This might be due to males' alexithymic incapaci
ty to seek help and/or their atypical depressive, acting out, or abusi
ve behaviour leading to rejection or misdiagnosis in the health care s
ystem. Consequently, underdiagnosis and undertreatment of male depress
ion exist and may explain the paradoxical fact that men in Sweden are
only half as often depressed as females but commit suicide up to five
times more. New sex-specific diagnostic and therapeutic tools as well
as sex-specific research concerning depression and suicidality are nee
ded.