LESSER ALKALOIDS OF COCAINE-BEARING PLANTS .2. 3-OXO-SUBSTITUTED TROPANE ESTERS - DETECTION AND MASS-SPECTRAL CHARACTERIZATION OF MINOR ALKALOIDS FOUND IN SOUTH-AMERICAN ERYTHROXYLUM COCA VAR COCA

Alkaloid extracts from the leaves of Erythroxylum coca var. coca, grow n in South America, were subjected to ion-pair chromatography and then to gas chromatographic-mass spectrometric analyses. Eight previously unreported trace level alkaloids were detected and characterized via c omparison to synthesized standards, including 3 alpha-benzoyloxytropan e, 3 alpha-phenylacetoxytropane, 3 beta-cis- and 3 beta-trans-cinnamoy loxytropane, 3 beta-2'-hydroxybenzoyloxytropane, 3 alpha-3',4',5'-trim ethoxybenzoyloxytropane, 3 alpha- and 3 eta-3',4',5'-trimethoxy-trans- cinnamoyloxytropane. Two additional alkaloids, 3 alpha- and 3 beta-3', 4',5'-trimethoxy-cis-cinnamoyloxytropane were also tentatively identif ied.