BACKGROUND: Laparoscopy is now expanding to surgery of intra-abdominal
solid organs such as splenectomy for hematologic diseases. The purpos
e of this study is to further demonstrate that laparoscopic splenectom
y is feasible for the surgeon, teachable for the resident, and benefic
ial to the patient and to revise prior contraindications to this minim
ally invasive approach. METHODS: Thirty-three consecutive cases of lap
aroscopic splenectomy were performed between May 1992 and March 1996.
The series included 21 females and 12 males with a median age of 42 ye
ars (range 19-19) and a median weight of 73 kg (range 36-115), Indicat
ions included: immune thrombocytopenic purpura (20), hemolytic anemia
(5), hereditary spherocytosis (4), infarction with abscess (1), Hodgki
n's lymphoma (1), Gaucher's disease (1), and AIDS-related thrombocytop
enia (1). Dissection was predominately performed with a new surgical i
nstrument, the harmonic shears, and main vessels were controlled with
clips. RESULTS: Thirty-two (97%) Of the cases were completed laparosco
pically, with (3%) conversion to control hilar bleeding. Four patients
underwent simultaneous cholecystectomy. The median spleen size was 13
cm (range 8-28) and median weight was 256 g (range 40-2100). Median o
perating time was 242 minutes (range 85-515). Morbidity occurred in 2
(6%) patients: ileus and small bowel obstruction. Median hospital stay
was 4 days (range 2-14). There was no mortality in our series. Median
follow-up was 20 months (range 1-46) with no evidence of late surgica
l complication or recurrent disease. CONCLUSION: Laparoscopic splenect
omy may be successful in cases previously considered contraindicated,
particularly splenomegaly and splenic infarct with abscess, it is a pr
ocedure that can be learned under appropriate guidance in academic cen
ters. (C) 1996 by Excerpta Medica, Inc.