ISOLATION OF A CDNA-ENCODING THE XENOPUS HOMOLOG OF MAMMALIAN CDC25A THAT CAN INDUCE MEIOTIC MATURATION OF OOCYTES

Authors
OKAZAKI K HAYASHIDA K IWASHITA J HARANO M FURUNO N SAGATA N
Citation
K. Okazaki et al., ISOLATION OF A CDNA-ENCODING THE XENOPUS HOMOLOG OF MAMMALIAN CDC25A THAT CAN INDUCE MEIOTIC MATURATION OF OOCYTES, Gene, 178(1-2), 1996, pp. 111-114
Citations number
15
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
178
Issue
1-2
Year of publication
1996
Pages
111 - 114
Database
ISI
SICI code
0378-1119(1996)178:1-2<111:IOACTX>2.0.ZU;2-T
Abstract
From a cDNA library of Xenopus laevis (XI) oocytes, we isolated a cDNA encoding a putative protein phosphatase homologous to mammalian Cdc25 A. Sequence analysis predicts that the XI cdc25A gene product (XI Cdc2 5A) consists of 521 amino acid residues and shares overall 55% identit y with human Cdc25A. When its mRNA is injected into Xl oocytes, Xl Cdc 25A can act as a potent M phase inducer.