DETERMINATION OF ARSENIC SPECIES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY HYDRIDE GENERATION (ULTRASONIC NEBULIZER) ATOMIC FLUORESCENCE SPECTROMETRY

A technique to determine four species of arsenic (As-III, As-V, dimeth ylarsinic (DMAs), and monomethylarsonic (MMAs) acids) where high-perfo rmance liquid chromatography was coupled Lo an atomic fluorescence spe ctrometer using an ultrasonic nebulizer as an interface has been furth er improved by the use of hydride generation. The effect of hydride co nditions on signal intensities has been Investigated. The detection li mits for As-III, As-V, DMAs, and MMAs were 2.5, 6, 3.2, and 2 ng, resp ectively (at 250 mm(3) volume injected). The linearity for all four ar senic species were in the range 25-1000 ng. (C) 1996 Academic Press. I nc.