The clinicopathological profiles of 419 patients with asymptomatic gas
tric cancer (AGC) first detected by gastric screening, were reviewed a
nd compared with those of the 1727 patients with symptomatic gastric c
ancer (SGC). The incidence of AGC increased gradually and has amounted
to 30% of the total resected cases in recent years. About 75% of AGC
cases were of early cancer and 84% were negative for lymph node metast
ases. In contrast, only 33% of SGC cases were of early cancer and 57%
were node positive. Curative resection was done in 97% of AGC and 75%
of SGC. The cumulative 5 and 10 year survival rates of patients with c
uratively resected AGC were 85.2% and 72.2%, respectively, while those
for patients with SGC were 66.8% and 55.4%. These data demonstrated t
hat most patients with asymptomatic gastric cancers could expect a cur
ative resection, i.e. have a better clinical outcome, than those with
symptomatic cancer.