P. Schnider et al., LONG-TERM OUTCOME OF PATIENTS WITH HEADACHE AND DRUG-ABUSE AFTER INPATIENT WITHDRAWAL - 5-YEAR FOLLOW-UP, Cephalalgia, 16(7), 1996, pp. 481-485
Thirty-eight patients with ''chronic daily'' headache and ergotamine a
nd/or analgesics abuse according to the criteria proposed by the Inter
national Headache Society were re-investigated 5 years after inpatient
drug withdrawal. At the end of the observation period, 19 patients (5
0.0%) had their headaches on only 8 days per month or less, 18 patient
s (47.4%) were free of symptoms or had only mild headaches. A close co
rrelation was found between the frequency of headache and the duration
of drug abuse, as well as between the intensity of headache and the n
umber of tablets taken per month. Frequency and intensity of headache
had changed within the first 2 years after withdrawal, but remained st
able afterwards. Fifteen patients (39.5%) reported on recurrent drug a
buse. Patients with migraine showed a tendency towards a better progno
sis compared to patients with tension-type headache or with combined m
igraine and tension-type headache. The results of this study highlight
the long-term efficacy of inpatient drug withdrawal in patients with
headache and ergotamine and/or analgesics abuse.