CHANGING DIETS AND LIFESTYLES contribute to an increase in the prevale
nce of cardiovascular disease and diabetes in Alaska Natives. To exami
ne the problem in detail, we have begun a systematic screening of vari
ous ethnic groups by carrying out a pilot study of Siberian Yupik Eski
mos ages 39 and over. Mean LDL and HDL levels were 157 mg/dl and 63 mg
/dl. Mean fasting insulin was 7.0 microunits/ml; and mean BMI, 27.1. F
asting insulin level was significantly related to both diastolic blood
pressure and fasting triglyceride levels, but not to systolic blood p
ressure, total cholesterol, LDL cholesterol, or HDL cholesterol levels
. Of the 66 people screened, 27% had evidence of hypertension.