GASTROESOPHAGEAL REFLUX - A DETERMINANT IN THE OUTCOME OF CAUSTIC ESOPHAGEAL BURNS

Deep circumferencial burns of the esophagus always result in stricture formation and obstruction of the lumen. The usual treatment of causti c esophageal strictures is long-term esophageal dilatations. A new met hod of treatment, long-term stenting of the strictured esophagus gave superior results when compared with the classic dilatation therapy (he ating rates, 68% v 33%; P < .01). Although success in the stent group was very satisfactory, the 32% failure rate requires explanation. In t he years between 1991 and 1993, 53 stent-treated patients were screene d for gastroesophageal reflux (GER). All patients were investigated wi th 24-hour ambulatory distal esophageal pHmetry. In 18 patients reflux index (RI) was found to be below 4. In 14 patients RI was between 4.1 and 19. In the final group of 21 patients RI was over 20 (minimum, 21 .8; maximum, 72.8). When these data were compared with the healing rat es of the patients, it was found that none of the 21 patients with RI over 20 responded to the described therapy. We conclude that the esoph agus, after a serious caustic insult, not only narrows but also shorte ns thus altering the lower esophageal sphincter function leading to se rious GER. Therefore all caustic esophageal burn patients should be sc reened for GER periodically during the dilatation or stent therapy pro grams, and GER should be controlled before RI approaches 20. Copyright (C) 1996 by W.B. Saunders Company.