Objective: To evaluate quality of life after prolonged multiple system
intensive care treatment in cardiac surgical patients, Design: A case
control study, Setting: Adult 12-bed thoracic intensive care unit (IC
U) at a university teaching hospital, Patients: Forty-seven patients s
urviving multiple organ failure requiring intensive care treatment for
>5 days (ICU group). Patients with a completely uncomplicated postope
rative course were matched to the study group with respect to gender,
age, and type and date of surgery. The Nottingham Health Profile was u
sed to assess quality of life at least 1 yr after complicated cardiac
surgery.Interventions: Quality of life measures were collected at leas
t 1 yr after discharge from the ICU, Measurements and Main Results: Se
venty-five percent of the patients in the ICU group suffered from mult
iple organ failure involving at least three organ systems, with a mean
stay in the ICU of 9.0 +/- 1.2 (SEM) days, Quality of life was consid
erably reduced in the ICU group, with a higher total mean score of all
dimensions of quality of life (22.7 +/- 2.6) compared with the contro
l group (13,2 +/- 2,4 [SEM]) (P < .01), The Nottingham Health Profile
score was higher in three of six dimensions of health-i.e., energy (p
< .05), physical mobility (p < .05), and emotional reactions (p < .05)
-compared with the control group. A higher percentage of patients repo
rted problems in three of six important activities of daily life-house
work (p < .05), hobbies (p < .01), and sex life (p < .01)-compared wit
h the control group. Conclusion: Patients treated with prolonged multi
ple system intensive care after heart surgery have a poor outcome with
respect to quality of life measured at least 1 yr after discharge fro
m the ICU.