THE SYNTHESIS OF 5-AZIDO-UTP AND UDP-PYRIDOXAL AND THEIR EFFECT ON THE CARBAMOYL-PHOSPHATE SYNTHETASE (CPS-II) IN THE MAMMALIAN MULTIENZYMEPOLYPEPTIDE CAD

Authors
ZHU LM CARREY EA
Citation
Lm. Zhu et Ea. Carrey, THE SYNTHESIS OF 5-AZIDO-UTP AND UDP-PYRIDOXAL AND THEIR EFFECT ON THE CARBAMOYL-PHOSPHATE SYNTHETASE (CPS-II) IN THE MAMMALIAN MULTIENZYMEPOLYPEPTIDE CAD, Bioorganic & medicinal chemistry letters, 6(21), 1996, pp. 2513-2518
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
21
Year of publication
1996
Pages
2513 - 2518
Database
ISI
SICI code
0960-894X(1996)6:21<2513:TSO5AU>2.0.ZU;2-J
Abstract
5-azidouridine-5'-triphosphate and UDP-pyridoxal have been synthesized using modified synthetic methods. The two synthetic UTP analogues, wi th commercially available analogues and chemicals have been tested for their effect on CPSase II in the mammalian multienzyme polypeptide CA D. Structure activity relationships are discussed. Copyright (C) 1996 Elsevier Science Ltd