GLYCO-S-NITROSOTHIOLS, A NOVEL CLASS OF NO DONOR COMPOUNDS

Authors
RAMIREZ J YU LB LI J BRAUNSCHWEIGER PG WANG PG
Citation
J. Ramirez et al., GLYCO-S-NITROSOTHIOLS, A NOVEL CLASS OF NO DONOR COMPOUNDS, Bioorganic & medicinal chemistry letters, 6(21), 1996, pp. 2575-2580
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
21
Year of publication
1996
Pages
2575 - 2580
Database
ISI
SICI code
0960-894X(1996)6:21<2575:GANCON>2.0.ZU;2-G
Abstract
Three novel glyco-S-nitrosothiol NO donor compounds 1, 2, and 3 have b een synthesized. These compounds outperform S-nitroso-N-acetylpenicill amine (SNAP) in aqueous solubility and stability, with and without EDT A and in the presence or absence of Cu2+. Copyright (C) 1996 Elsevier Science Ltd