ANAPLASTIC (MALIGNANT) GANGLIOGLIOMA ARISING FROM HETEROTOPIC GREY-MATTER NODULES

Anaplastic ganglioglioma is a rare malignant neoplasm. The short clini cal course and the anaplastic histological features are characteristic s of malignant ganglioglioma. Immunohistochemistry is necessary for th e final diagnosis. The MRI appearances are described here for the firs t time in literature. Nodular grey matter heterotopias had been demons trated and the patient developed an anaplastic ganglioglioma two years later, on the same place where the grey matter heteropias had been se en. This finding supports the hypothesis that these tumours may arise from grey matter nodules.