LONG-ACTING IOMIR (ISRADIPIN) IN MANAGING MILD AND MODERATE ESSENTIAL-HYPERTENSION

24-hour monitoring of arterial pressure has been performed outpatientl y in 20 subjects with mild or moderate essential hypertension using po rtable system SpaceLabs 90207. The design of the study implied 2 weeks of observation without any treatment followed by a 4-week course of l omir SRO-5 plus a 2-week course of lomir administration in a double do se. Control examination was performed at the end of each period. It wa s established that a 4-week lomir course results in a lowering of syst olic and diastolic pressure by 8.4+-2.1 and 6.9+-1.3 mm Hg, respective ly. Double-dose lomir was also effective: a fall in both systolic and diastolic pressure by 15.6+-3.2 and 8.1+-1.8 mm Hg, respectively, was achieved.