An. Parkhomenko et al., ANTIOXIDANT TRIMETASIDINE (PREDUKTAL) IN COMBINED THERAPY OF ACUTE MYOCARDIAL-INFARCTION, Terapevticeskij arhiv, 68(9), 1996, pp. 47-52
86 patients with acute transmural and macrofocal myocardial infarction
received combined treatment which included standard therapy (thrombol
ytic drugs, beta-blockers, APP inhibitors, nitrates, aspirin) and anti
oxidant trimetasidine. The addition of the latter was beneficial: the
size of the myocardial lesion was limited, electrical unstability of t
he heart attenuated, early dilatation of the left heart prevented.