Dg. Cruger et al., EARLY PRENATAL-DIAGNOSIS - STANDARD CYTOGENETIC ANALYSIS OF CELOMIC CELLS OBTAINED BY COELOCENTESIS, Prenatal diagnosis, 16(10), 1996, pp. 945-949
Coelomic fluid samples (n=30) were obtained from normal pregnancies be
tween 6.0 and 10.0 weeks and attempts to culture the coelomic cells we
re made. With one culture system, nine of ten samples were cultured an
d successful cytogenetic analysis was performed. There have been no pr
evious reports of traditional cytogenetic analysis of coelomic cells a
nd this might be the breakthrough for coelocentesis as a future method
for early prenatal diagnosis.