MATERNAL UNIPARENTAL DISOMY FOR CHROMOSOME-2 IN ASSOCIATION WITH CONFINED PLACENTAL MOSAICISM FOR TRISOMY-2 AND SEVERE INTRAUTERINE GROWTH-RETARDATION

Authors
WEBB AL STURGISS S WARWICKER P ROBSON SC GOODSHIP JA WOLSTENHOLME J
Citation
Al. Webb et al., MATERNAL UNIPARENTAL DISOMY FOR CHROMOSOME-2 IN ASSOCIATION WITH CONFINED PLACENTAL MOSAICISM FOR TRISOMY-2 AND SEVERE INTRAUTERINE GROWTH-RETARDATION, Prenatal diagnosis, 16(10), 1996, pp. 958-962
Citations number
11
Categorie Soggetti
Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
16
Issue
10
Year of publication
1996
Pages
958 - 962
Database
ISI
SICI code
0197-3851(1996)16:10<958:MUDFCI>2.0.ZU;2-U
Abstract
We report a liveborn infant with severe intrauterine growth retardatio n and renal failure, delivered following detection of non-mosaic triso my 2 by chorionic villus biopsy in the first trimester. Detailed analy sis post-delivery indicated apparent complete trisomy 2, of the chorio nic tissues, with a chromosomally normal infant demonstrating maternal uniparental disomy for chromosome 2.