D. Dewhurst et al., AN INTERACTIVE COMPUTER-PROGRAM TO REPLACE IN-VIVO EXPERIMENTS ON RAT-BLOOD PRESSURE FOR TEACHING UNDERGRADUATE STUDENTS, ATLA. Alternatives to laboratory animals, 24(5), 1996, pp. 707-714
An interactive computer program is described, which presents simulated
data for a range of tutor-designed, structured investigations perform
ed in vivo in the anaesthetised rat. It is aimed at undergraduate stud
ents of pharmacology, and is designed to teach various aspects of card
iovascular pharmacology and to provide an alternative to performing th
e practical procedure on live animals. In addition to providing simula
ted data, the program covers several other aspects related to the live
practical, for example, UK Home Office Licence requirements, anaesthe
sia of the animals, cannulation procedures and the apparatus used. It
also contains suggested student tasks for each experiment, making it s
uitable for independent learning. The program is written for IBM-compa
tible PCs running Windows(TM) and makes use of several features to enh
ance interactivity and presentation, i.e. high-resolution colour graph
ics, animation, interactive questions (multiple choice, drag and drop,
True/False), problem-solving exercises and simulations. It has been e
valuated with final year BSc (Hens) Pharmacology students at one UK un
iversity, where is was used to prepare students for the live animal pr
actical. The results of this small study were largely favourable.