Octreotide is a synthetic analogue of somatostatin with therapeutic ap
plications in a variety of endocrine and gastrointestinal disorders, W
e report a patient with acromegaly who developed acute hepatocellular
liver injury after receiving two 0.1-mg doses of octreotide, The drug
causality was confirmed by rechallenge. To our knowledge this is the s
econd reported case in the literature.