Distinguishing between osteomyelitis and neuropathic osteoarthropathy
of the foot frequently presents a clinical and radiologic challenge in
patients with diabetes. Magnetic resonance (MR) imaging was performed
in 26 diabetic patients to observe changes in signal intensity in the
complicated diabetic foot. In every patient with osteomyelitis (n = 1
3), signal intensity abnormalities were seen within the bone marrow (l
ow signal intensity on T1-weighted images and high signal intensity on
T2-weighted images in 12 cases). Most of these patients had cortical
lesions (n = 9) or associated soft-tissue infection (n = 12). Normal b
one marrow signal intensity was observed in three of the four patients
without osteomyelitis. Characteristic MR imaging findings (decreased
signal intensity in bone marrow regardless of pulse sequence) were see
n in patients with chronic neuropathic osteoarthropathy (n = 7), who w
ere easily distinguished from patients with osteomyelitis. Conversely,
in patients with acutely evolving neuropathic osteoarthropathy (n = 2
), signal intensity changes within the bone marrow were similar to tho
se observed in osteomyelitis, leading to potential diagnostic pitfalls
. Familiarity with MR imaging findings observed in osteomyelitis and n
europathic osteoarthropathy can help identify these two entities, allo
wing early diagnosis and appropriate therapy.