MULTINUCLEATE CELL ANGIOHISTIOCYTOMA - RE PORT OF 6 CASES

Multinucleate cell angiohistiocytoma is a recently described entity. I t is a benign vascular proliferation. Clinically, it is characterized by violaceous red papules, often mimicking Kaposi's salcoma. Acral sit es and face were the commonest sires. The six patient's age tvas betwe en 41 and 64 years and sex ratio tvas equal. Microscopic features were an increased number of blood vessels together with mononucleated and multinucleated histiocyte-like cells with scalloped borders. Staining of mononucleated cells with CD68, anti vimentin and anti factor XIIIa antibodies emphasized a fibrohistiocytic origin. Loss of factor XIIIa expression in multinucleate cells gets clue to think thar these cells are dedifferenciated.