The aim of this study was to describe the clinical characteristics and
the polysomnographic findings of a sample of patients affected by sle
ep-related painful erections (SRPE). In a 6-y period 18 patients were
diagnosed as having SRPE. The mean age at the onset of the disease was
39.8 +/- 11.6 y and the mean duration of SRPE was 5.4 +/- 3.5 y. Acco
rding to ICSD criteria, about 60% of patients had a severe form of the
disease. None of the patients met any DSM IV Axis-I and Axis-II diagn
oses. Twelve patients complained of excessive daytime sleepiness. SRPE
patients, compared to age-matched controls, showed a reduced sleep ef
ficiency, an increased wake after sleep onset and a reduced percentage
of REM sleep. This study confirms that in SRPE there are no clear pre
disposing factors, no familial pattern, but REM sleep fragmentation. C
oncerning the pharmacological treatment, in the history of patients, p
ropranolol and paroxetine, but not amitriptiline and lorazepam, showed
a temporary efficacy in some patients.