Cl. Matwichuk et al., USE OF TECHNETIUM TC 99M SESTAMIBI FOR DETECTION OF A PARATHYROID ADENOMA IN A DOG WITH PRIMARY HYPERPARATHYROIDISM, Journal of the American Veterinary Medical Association, 209(10), 1996, pp. 1733
Double-phase parathyroid gland scintigraphy using technetium Tc 99m se
stamibi, correctly identified the existence and location of a parathyr
oid adenoma in a dog with primary hyperparathyroidism. The parathyroid
adenoma was removed surgically 2 days after scintigraphy. An area of
focal radionuclide uptake persisted in the region corresponding to the
left external parathyroid gland in the delayed-phase image. Delayed-p
hase images from 3 healthy dogs and a dog with hypercalcemia of malign
ancy caused by lymphoma did not reveal an area of persistent radiotrac
er uptake. Double-phase parathyroid gland scintigraphy, using Tc-99m-s
estamibi, is a simple, rapid, noninvasive test, which can be used for
detection and localization of parathyroid adenomas in hypercalcemic do
gs. It also can help to differentiate these dogs from dogs with hyperc
alcemia of malignancy.