Dc. Bills et al., INTRACRANIAL ARTERIOVENOUS-MALFORMATIONS IN CHILDHOOD - PRESENTATION,MANAGEMENT AND OUTCOME, Journal of clinical neuroscience, 3(3), 1996, pp. 220-228
Cases of true intracranial arteriovenous malformations (AVMs) presenti
ng over a 25 year period were reviewed in order to achieve a better un
derstanding of the behaviour and management of AVMs in children, There
were 69 cases, presenting with haemorrhage (78%), seizures (13%) card
iac failure (3%) and focal signs with or without headache (6%), It was
less common to present under six years of age, CT scanning, where per
formed, always demonstrated an abnormality, but this was suggestive of
an AVM in less than one third. By contrast, angiography defined the l
esion in 82% of initial studies, 59 patients underwent a surgical proc
edure directed at their AVM or an associated haematoma, Total AVM exci
sion was obtained in 65%, with none of these later rebleeding, Three p
atients presenting solely with seizures were not operated upon initial
ly but underwent successful resections of their lesions after later ha
emorrhages, There were 6 (9%) deaths in the series, with focal deficit
s in 52% of survivors at last follow up, In the operative group these
figures were 3% and 51%, respectively, None of the eight patients oper
ated upon prior to a clinical bleed suffered a new neurological defici
t, The role of stereotactic radiosurgery, although not used in any of
our cases, is discussed. We believe that our results support an aggres
sive surgical approach to childhood AVMs, regardless of presentation,
given the significant risk of morbidity from a later bleed, and the la
ck of a clearly better outcome with expectant management or irradiatio
n. (C) Pearson Professional 1996