DIASTEREOSPECIFIC EPOXIDATION AE KINETIC RESOLUTION OF CIS TRANS-2,6-DIMETHYLBENZYLIDENE CYCLOHEXANE AND SOLUTION CONFORMATION OF 4,8-DIMETHYL-2-PHENY1-1-OXASPIRO[2.5]OCTANE/

Authors
GARDINER JM NORRET M SADLER IH
Citation
Jm. Gardiner et al., DIASTEREOSPECIFIC EPOXIDATION AE KINETIC RESOLUTION OF CIS TRANS-2,6-DIMETHYLBENZYLIDENE CYCLOHEXANE AND SOLUTION CONFORMATION OF 4,8-DIMETHYL-2-PHENY1-1-OXASPIRO[2.5]OCTANE/, Tetrahedron letters, 37(46), 1996, pp. 8447-8450
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
46
Year of publication
1996
Pages
8447 - 8450
Database
ISI
SICI code
0040-4039(1996)37:46<8447:DEAKRO>2.0.ZU;2-Z
Abstract
Epoxidation using a (salen)Mn catalyst shows complete selectivity betw een 2,6-trans and 2,6-cis dimethylbenzylidene cyclohexanes, is diaster eospecific, and exhibits a kinetic resolution with k(rel)=5 Stereochem istry and conformation of the product 4,8-dimethyl-2-pheny-1-1-oxaspir o[2.5]octane were determined by DQF-COSY and nOe difference measuremen ts at 600MHz. Copyright (C) 1996 Elsevier Science Ltd