GEOGRAPHIC CLUSTERING OF HUMAN Y-CHROMOSOME HAPLOTYPES

Citation
Ar. Linares et al., GEOGRAPHIC CLUSTERING OF HUMAN Y-CHROMOSOME HAPLOTYPES, Annals of Human Genetics, 60, 1996, pp. 401-408
Citations number
33
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00034800
Volume
60
Year of publication
1996
Part
5
Pages
401 - 408
Database
ISI
SICI code
0003-4800(1996)60:<401:GCOHYH>2.0.ZU;2-P
Abstract
Five polymorphic markers on the Y-chromosome (mostly microsatellites) were typed in 121 individuals from 13 populations around the world. Wi th these markers 78 different haplotypes were detected. Haplotypes pre sent more than once tend to be shared by individuals from the same pop ulation or continent. A reconstruction of haplotype phylogeny also ind icates significant geographic structure in the data. Based on the simi larity of the haplotypes, population relationships were examined and f ound to be largely concordant with those obtained with other markers. Even though the sample size and the number of markers are small, there is very significant clustering of the haplotypes by continent of orig in.