S. Corrao et al., ANALYSIS OF 24-H NONINVASIVE AMBULATORY BLOOD-PRESSURE PROFILES BY A 3RD-DEGREE POLYNOMIAL APPROACH, Journal of cardiovascular diagnosis and procedures, 13(4), 1996, pp. 237-242
Citations number
8
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging","Cardiac & Cardiovascular System
Extensive experience of the circadian variation of blood pressure (BE)
has been reported. But some problems exist concerning the correct and
satisfactory evaluation of 24-h BP profiles, A well-known approach is
the Halberg's ''cosinor'' method. But it could be considered inadequa
te for blood pressure recordings because it is based on a rigid model
that does not practically fit empirical data, We suggest an approach b
ased on a cubic function as a suitable method for such an analysis, Ou
r investigation studied the behavior of 24-h blood pressure by a model
where the function f(t) is a third-degree polynomial, We recruited 52
untreated patients affected by essential hypertension, Ambulatory BP
recordings were made using a portable noninvasive system, Data were an
alyzed by a computerized procedure for both estimating parameters of t
he cubic-polynomial model and obtaining conventional and function-deri
ved parameters, Eleven of 52 hypertensives showed no common rhythm: 8
patients had no statistically significant rhythm and 3 had a reversed
rhythm, The 8 of 11 hypertensives who had no statistically significant
rhythms were also ''nondippers'' according to the criteria of Verdecc
hia et al.((8)) The remaining 41 patients were matched and compared to
41 normotensive subjects, In general, function-derived parameters str
essed differences between the two groups more than the conventional on
es, We suggested an analysis of 24-h BP data based on a cubic function
model, We verified that such a methodology is feasible, At the moment
, it seems a useful approach for clinical investigation.