NEURONAL PATHFINDING AND RECOGNITION - ROLES OF CELL-ADHESION MOLECULES

Neurons contact their neighbors through a diverse array of cell adhesi on and other surface molecules. These molecules can exhibit highly reg ulated patterns of expression, underscoring their multiple roles in es tablishing specific interactions between neurons and their environment . Recent studies are beginning to ask how these membrane-bound neural recognition molecules interact with each other and intracellular signa ling pathways within an individual neuronal growth cone, and direct th e formation of neural connections during development. (C) 1996 Academi c Press. Inc.