Msi. Makki et Hm. Faidallah, SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW FUSED THIAZOLO[4,5-D]PYRIDAZINE DERIVATIVES, Journal of the Chinese Chemical Society, 43(5), 1996, pp. 433-438
The synthesis of thiazolo[4,5-d]pyridazines and the unknown ring syste
ms, thiazolo[4,5-d]-1,2,4-triazolo- and tetrazolo[4,3-b]pyridazines as
well as thiazolo[4,5-d]pyridazino[2,3-c]2H triazines, has been achiev
ed according to different pathways. Biological testing of the new tric
yclic heterocycles revealed that some of these compounds possess remar
kable antibacterial activity.