A replication is reported of a three-factor-active, withdrawn, unreali
ty-structure of schizotypy measured with the Schizotypal Personality Q
uestionnaire (SPQ) in the normal population, a structure which has clo
se affinities with a three-syndrome model of schizophrenia. Cognitive
asymmetry patterns and arousal scales are found in the companion repor
t-Part II in this issue of the Schizophrenia Bulletin. Here the withdr
awn factor-loneliness and constricted affect-was also complemented by
the physical anhedonia scale. The original sample (1995) was then comb
ined with the replication sample to examine associations with the dime
nsions of extraversion-introversion, neuroticism, and psychoticism. In
troversion loaded on the first withdrawn factor. The second unreality
factor-unusual perceptions, magical beliefs, and ideas of reference-wa
s unrelated to the Eysenck dimensions. Psychoticism loaded on the thir
d active factor-eccentricity and odd speech. Neuroticism formed a four
th, nonspecific factor with social anxiety and suspiciousness. Insuffi
ciencies in current measures of the structure of schizotypy and schizo
phrenia are discussed. These include the absence of activity-arousal f
rom the SPQ, the limited assessment of cognitive disorganization in sc
hizotypy, and its heterogeneity in schizophrenia. The history of the a
ctive-withdrawn classification and its importance in further elucidati
on of schizotypy and schizophrenia are outlined.