We report on three patients with severe Graves' dermopathy who were tr
eated with octreotide despite a negative octreotide scintigraphy. One
patient showed a complete recovery while two others had a partial resp
onse. In contrast to active Graves' ophthalmopathy, an octreotide scin
tigraphy appears not to be useful for pretreatment identification of p
atients with Graves' dermopathy who are likely to respond to octreotid
e treatment.