EVALUATING THE CELL-DYN(R)-3500 HEMATOLOGY ANALYZER IN AN ACUTE GENERAL-HOSPITAL

The CELL-DYN(R) 3500 (CD3500) (Abbott Diagnostics Division, Santa Clar a, CA, USA) is a multiparameter, automated haematology analyser system capable of producing 22 haematological parameters including a screeni ng five-part differential. The evaluation was performed in a recently expanded acute care general hospital. Studies of linearity, carryover and precision were acceptable and within manufacturer's stated limits, Correlation of CD3500 with manual differential counts were good excep t for the basophil count, The white cell nagging system had a sensitiv ity of 83.6% and specificity of 88.9% with 85.6% agreement. The platel et nagging system also had comparable sensitivity and specificity rate of 88.4% and 94.5% and agreement rate of 92.2%. The overall false pos itive rate and false negative rate for both the white cell and platele t flags combined were 8.6% and 10.3%. All samples provided a different ial with no rejection experienced. The MAPSS technology, together with the extended lyse mode and the investigational nine-part differential provides potential for future development in WBC differential.