BACKGROUND. Psychotic symptoms include a variety of disturbances in pe
rception, reality testing, speech, and behavior. We examine the preval
ence, distribution, treatment, and functional impairment associated wi
th psychotic symptoms in primary care patients. METHODS. Data are draw
n from a recent study of adult primary care patients (N=1001) in a lar
ge, urban, prepaid group practice. At the medical visit, patients comp
leted a questionnaire that probed demographic characteristics, health
status, and mental health care utilization. Following the visit, patie
nts received a telephone-administered, structured psychiatric intervie
w that included 11 psychotic symptoms, Medication prescription data we
re also available. Comparisons are presented of patients with and with
out psychotic symptoms. RESULTS. Thirty-seven (3.7%) patients reported
one or more psychotic symptoms, most commonly a belief that others we
re spying on or following them (n=16). As compared with patients witho
ut psychotic symptoms, a larger proportion of the patients with psycho
tic symptoms reported mental health-related work loss (54.1% vs 17.9%,
P<.0001), suicidal ideation (21.6% vs 2.6%, P<.0001), major depressiv
e disorder (32.4% vs 6.3%, P<.0001), bipolar disorder (29.7% vs 1.2%,
P<.0001), and several other mental disorders, An antipsychotic medicat
ion had been prescribed during the previous 17 to 20 months for only t
wo (5.4%) of the patients with psychotic symptoms. CONCLUSIONS, Psycho
tic symptoms were relatively common (3.7%) in this practice and were s
trongly associated with functional impairment and affective, anxiety,
or substance use disorders. Primary care physicians are encouraged to
examine patients with these mental disorders for the presence of psych
otic symptoms.