MALIGNANT PLEURAL MESOTHELIOMA FOLLOWING RADIOTHERAPY FOR HODGKINS-DISEASE

Second neoplasms following chemotherapy and radiotherapy for Hodgkin's disease have been extensively described, including acute myeloblastic leukemia, non Hodgkin's lymphomas and various solid tumors. We report malignant pleural mesothelioma occurring 17 years after mantle radiot herapy and MOPP chemotherapy for Hodgkin's disease. According to Cahan 's criteria, this mesothelioma may be considered as treatment-related Fourteen similar cases have been previously published. Post-radiation mesothelioma might be characterised by limited stage ar diagnosis and might be surgically removed at presentation.