REACTION OF SOME ALPHA-OXOPHENYLHYDRAZONES WITH 2-AMINO-1,1,3-TRICYANOPROPENE AND DIETHYL 1-CYANO-2-AMINOPROPENE-1,3-DICARBOXYLATE - SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED PYRIDINE, PYRIDAZINE AND CINNOLINEDERIVATIVES

alpha-Oxophenylhydrazones 1, 9 and 18 reacted with enaminonitrile 4 to yield pyridopyridine, pyridine and pyridopyridazine derivatives 3, 11 and 19 respectively, while hydrazone 18 reacted with enaminoester 21 to yield the pyridopyridine derivative 22; the activity of the methyl function in 3, 11, 19 and 22 was tested by reaction with benzaldehyde followed by cyclization to give the polycyclic compounds 7, 13, 20 and 24, respectively.