The use of prokinetic agents by pediatric patients, geriatric patients
, and patients taking other drugs that may affect or be affected by th
e prokinetic agent is reviewed. The use of such agents to treat motili
ty disorders has expanded over the past few years. These agents may be
administered to patients who have special physiologic considerations,
have other diseases, or require concomitant drug therapy. The appropr
iate use of prokinetic agents in these groups requires an understandin
g of the unique dosage considerations that may be necessary to ensure
safe, effective therapy.