SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 10-N-ARYLAMINOMETHYL-1,3,7,9-TETRACHLORO H-PHENOTHIAZINES/

Authors
PUROHIT DM MEHTA DS SHAH VH
Citation
Dm. Purohit et al., SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 10-N-ARYLAMINOMETHYL-1,3,7,9-TETRACHLORO H-PHENOTHIAZINES/, Heterocyclic communications, 2(5), 1996, pp. 469-474
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocyclic communications → ACNP
ISSN journal
07930283
Volume
2
Issue
5
Year of publication
1996
Pages
469 - 474
Database
ISI
SICI code
0793-0283(1996)2:5<469:SAAAO1>2.0.ZU;2-L
Abstract
The titled compounds have been synthesised by the reaction of formalde hyde and arylamine with 1,3,7,9-tetracholoro/H-phenothiazines in the p resence of hydrochloricacid (Mannich reaction). The constitution of th e products have been delineated by spectral data. The products have be en evaluated for their antimicrobial activity. Some of the compounds h ave found to be having comparable activity with standard drugs viz. Am picillin, Chloramphanicol, Norfloxacin and Griseofulvin.