BONE-MARROW TRANSPLANTATION IN CHRONIC GVHD AND AUTOIMMUNE-DISEASES

Citation
M. Andolina et al., BONE-MARROW TRANSPLANTATION IN CHRONIC GVHD AND AUTOIMMUNE-DISEASES, Bone marrow transplantation, 18, 1996, pp. 145-147
Citations number
7
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
ISSN journal
02683369
Volume
18
Year of publication
1996
Supplement
2
Pages
145 - 147
Database
ISI
SICI code
0268-3369(1996)18:<145:BTICGA>2.0.ZU;2-2
Abstract
The same ex vivo marrow's treatment that we used in mismatched BMT (in cubation with vincristine and methylprednisolone) was used in two pati ents with chronic GVHD and in one patient with PRCA. The conditioning regimen with cyclophosphamide and ALG was aimed to hill only the patie nt's lymphocytes, and did not cause a deep myeloid aplasia. The patien ts achieved a clear improvement of their symptoms.