S. Rimbach et al., COMPARISON OF IN-VITRO FALLOPOSCOPY WITH TUBAL HISTOLOGY IN THE DIAGNOSIS OF FALLOPIAN-TUBE PATHOLOGY, Human reproduction, 11(10), 1996, pp. 2130-2133
In order to assess the diagnostic quality of falloposcopy in relation
to pathomorphology, a consecutive series of 30 Fallopian tubes obtaine
d from surgical salpingectomy cases were prospectively examined by in-
vitro falloposcopy and histology. Falloposcopy was performed using an
over-the-wire catheterization system and a 0.5 mm falloposcope with 30
00 pixels. Assessment of the specimens included the description of lum
en geometry, intraluminal changes and status of the mucosal surface, F
alloposcopy classified 14 tubes as normal and 16 pathological, Histolo
gical resulted in 17 normal versus 13 pathological tubes, Pathologies
included lumen obstructions and dilatations, intraluminal synechiae an
d mucosal damage, Sensitivity and specificity of falloposcopy were cal
culated to be 0.85 and 0.71; positive and negative predictive values w
ere 0.69 and 0.86. It was concluded that falloposcopic findings indeed
reflect and successfully differentiate normal and pathological condit
ions allowing adequate and reproducible image interpretation, However
variations of the diagnostic accuracy with the type of pathology and t
he tubal segment have to be taken into account before clinical consequ
ences are drawn from a falloposcopic investigation.