A TICK HOMOLOG OF THE HUMAN KI NUCLEAR AUTOANTIGEN

Authors
PAESEN GC NUTTALL PA
Citation
Gc. Paesen et Pa. Nuttall, A TICK HOMOLOG OF THE HUMAN KI NUCLEAR AUTOANTIGEN, Biochimica et biophysica acta, N. Gene structure and expression, 1309(1-2), 1996, pp. 9-13
Citations number
28
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1309
Issue
1-2
Year of publication
1996
Pages
9 - 13
Database
ISI
SICI code
0167-4781(1996)1309:1-2<9:ATHOTH>2.0.ZU;2-G
Abstract
A clone isolated from a tick salivary gland cDNA library encodes a hom ologue of the human Ki lupus autoantigen, a protein of unknown functio n that is related to the subunits of the PA28 proteasome activator. Th e Ki sequences appear to be well conserved between mammals and inverte brates, with 55% identity between the tick and human primary structure s. This is the first report of a Ki homologue in invertebrates.